In 2009, PacBio published a paper expanding the principle into a full-blown sequencing technique. Once again, each nucleotide was labeled with a different colored fluorophore detectable by the ZMW to determine which base had been incorporated. The fluorophores were attached such that they would be cleaved off during the chemical reaction incorporating the base into the growing DNA strand; they would then diffuse out of the ZMW so that the next fluorophore could be detected. Sequencing took place on a chip with many wells simultaneously — a different type of parallelization where each well detected a single DNA molecule undergoing the same basic chemical reaction.
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志愿者的无偿服务，对医院来说，是实实在在的“成本利器”。虽然具体财务数据未公开，但我们可以通过服务时间，大致算出它的价值：
FT Edit: Access on iOS and web，详情可参考同城约会
Фото: Another77 / Shutterstock / Fotodom。关于这个话题，体育直播提供了深入分析
“Interesting” means that the change clearly opens new possibilities, improves